STRIVE Report 79 - A Human Blood Barrier Model for Screening Nanoparticle Uptake and Access.
Summary: STRIVE Report 79 - Michelle Nic Raghnaill, Meredith Brown, Dong Ye, Mattia Bramini, Kenneth Dawson and Iseult Lynch
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Nanomaterials are receiving increasing attention for their promise as engineering and biomedical revolutions of the 21st century. The rapid proliferation of many different engineered nanomaterials can, however, represent a hazard to human health, in occupational settings and possibly also for the population at large through exposure to nanomaterials via the environment. There is thus a strong need to develop scientific knowledge for use by industrials to develop safer nano-products and by regulators to control environmental and occupational exposures and limit risks. These efforts will allow a sustainable development of this growing field of economical activity.
A leading research group in UCD have examined the behaviour of model nanomaterials in relation to their transport across the blood brain barrier and outlined the need for mandatory reporting of their use by industry to enable exposure monitoring of humans and the environment.